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KMID : 0351619750160020153
Kyungpook Medical Journal
1975 Volume.16 No. 2 p.153 ~ p.158
Studies on the Circadian Variation of Phosphoenolpyruvate carboxykinase Activity in Chicken Liver


Abstract
This sudy is to observe the circadian. variation of chicken liver phosphoenolpyruvate carboxykinase (EC 4.1.1.32) activity and to analyse the influence¢¥ of fasting, actinomyciin D, and glucc:~e. The results obtained were summeiized as follows;
1. The enzyme activity generally exhibited annual rhythr.~ic variation with the high activity in the cold season (Dec. -Apr.) and the low activity in the hct season(May-Vov. ), thcugh tpe ranges of the activity were broad:
2. The enzyme also showed a diurnal variation with a crest at 0800 aad trough at 20~~, though the amplitude varied with the season.
3. The circadian rhythm of the enzyrne activity varied in reversed phas;, with fasting ^r cLanges of feeding time. Cirdadian increase of tl~e enzymE~ activity vas inhibtied by actinomycin D and glucose.
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